[1994-1999][2000-2004][2005-2009][2010-2014][2015-2019][2020-]

2022年
1. Hojo H, Saito T, He X, Guo Q, Onodera S, Azuma T, Koebis M, Nakao K, Aiba A, Seki M, Suzuki Y, Okada H, Tanaka S, Chung UI, McMahon AP, Ohba S.
Runx2 regulates chromatin accessibility to direct the osteoblast program at neonatal stages.
Cell Rep., 40, 111315, 2022

2. Abe YO, Yoshitane H, Kim DW, Kawakami S, Koebis M, Nakao K, Aiba A, Kim JK, Fukada Y.
Rhythmic transcription of Bmal1 stabilizes the circadian timekeeping system in mammals.
Nat Commun., 13, 4652, 2022

3. Hiraike Y, Tsutsumi S, Wada T, Oguchi M, Saito K, Nakamura M, Ota S, Koebis M, Nakao H, Aiba A, Nagano G, Ohno H, Oki K, Yoneda M, Kadowaki T, Aburatani H, Waki H, Yamauchi T.
NFIA determines the cis-effect of genetic variation on Ucp1 expression in murine thermogenic adipocytes.
iScience, 25, 104729, 2022

4. Harbers M, Nakao H, Watanabe T, Matsuyama K, Tohyama S, Nakao K, Kishimoto Y, Kano M, Aiba A.
mGluR5 Is Substitutable for mGluR1 in Cerebellar Purkinje Cells for Motor Coordination, Developmental Synapse Elimination, and Motor Learning.
Cells, 11, 2004, 2022

5. Mori K, Koebis M, Nakao K, Kobayashi S, Kiyama Y, Watanabe M, Manabe T, Iino Y, Aiba A.
Loss of calsyntenin paralogs disrupts interneuron stability and mouse behavior.
Mol Brain, 15, 23, 2022

2021年
1. Abe Y, Nakao H, Goto M, Tamano M, Koebis M, Nakao K, Aiba A.
Efficient marmoset genome engineering by autologous embryo transfer and CRISPR/Cas9 technology.
Sci Rep., 11, 20234, 2021

2. Hasegawa K, Takenaka N, Tanida K, Chan MP, Sakata M, Aiba A, Satoh T.
Atrophy of White Adipose Tissue Accompanied with Decreased Insulin-Stimulated Glucose Uptake in Mice Lacking the Small GTPase Rac1 Specifically in Adipocytes.
Int J Mol Sci., 22, 10753, 2021

3. Yamasaki M, Aiba A, Kano M, Watanabe M.
mGluR1 signaling in cerebellar Purkinje cells: Subcellular organization and involvement in cerebellar function and disease.
Neuropharmacology, 194, 108629, 2021

4. Kawarada L, Fukaya M, Saito R, Kassai H, Sakagami H, Aiba A.
Telencephalon-specific Alkbh1 conditional knockout mice display hippocampal atrophy and impaired learning.
FEBS Lett., 595, 1671-1680, 2021

5. Saito R, Miyoshi C, Koebis M, Kushima I, Nakao K, Mori D, Ozaki N, Funato H, Yanagisawa M, Aiba A.
Two novel mouse models mimicking minor deletions in 22q11.2 deletion syndrome revealed the contribution of each deleted region to psychiatric disorders.
Mol Brain, 14, 68, 2021

6. Arioka Y, Shishido E, Kushima I, Suzuki T, Saito R, Aiba A, Mori D, Ozaki N.
Chromosome 22q11.2 deletion causes PERK-dependent vulnerability in dopaminergic neurons.
EBioMedicine, 63, 103138, 2021

2020年
1. Morishita H, Kanda Y, Kaizuka T, Chino H, Nakao K, Miki Y, Taketomi Y, Guan JL, Murakami M, Aiba A, Mizushima N.
Autophagy Is Required for Maturation of Surfactant-Containing Lamellar Bodies in the Lung and Swim Bladder.
Cell Rep., 33, 108477, 2020

2. Nagahama K, Sakoori K, Watanabe T, Kishi Y, Kawaji K, Koebis M, Nakao K, Gotoh Y, Aiba A, Uesaka N, Kano M.
Setd1a Insufficiency in Mice Attenuates Excitatory Synaptic Function and Recapitulates Schizophrenia-Related Behavioral Abnormalities.
Cell Rep., 32, 108126, 2020

3. Toyoda Y, Takada T, Miyata H, Matsuo H, Kassai H, Nakao K, Nakatochi M, Kawamura Y, Shimizu S, Shinomiya N, Ichida K, Hosoyamada M, Aiba A, Suzuki H.
Identification of GLUT12/SLC2A12 as a urate transporter that regulates the blood urate level in hyperuricemia model mice.
Proc Natl Acad Sci USA., 117, 18175-18177, 2020

4. Saito R, Koebis M, Nagai T, Shimizu K, Liao J, Wulaer B, Sugaya Y, Nagahama K, Uesaka N, Kushima I, Mori D, Maruyama K, Nakao K, Kurihara H, Yamada K, Kano M, Fukada Y, Ozaki N, Aiba A.
Comprehensive analysis of a novel mouse model of the 22q11.2 deletion syndrome: a model with the most common 3.0-Mb deletion at the human 22q11.2 locus.
Transl Psychiatry, 10, 35, 2020

5. Kurano M, Tsukamoto K, Shimizu T, Kassai H, Nakao K, Aiba A, Hara M, Yatomi Y.
Protection Against Insulin Resistance by Apolipoprotein M/Sphingosine-1-Phosphate.
Diabetes, 69, 867-881, 2020

2019年
1. Narushima M, Yagasaki Y, Takeuchi Y, Aiba A, Miyata M.
The metabotropic glutamate receptor subtype 1 regulates development and maintenance of lemniscal synaptic connectivity in the somatosensory thalamus.
PLoS One, 14, e0226820, 2019

2. Kumita W, Sato K, Suzuki Y, Kurotaki Y, Harada T, Zhou Y, Kishi N, Sato K, Aiba A, Sakakibara Y, Feng G, Okano H, Sasaki E.
Efficient generation of Knock-in/Knock-out marmoset embryo via CRISPR/Cas9 gene editing.
Sci Rep., 9, 12719, 2019

3. Ueyama T, Sakuma M, Nakatsuji M, Uebi T, Hamada T, Aiba A, Saito N.
Rac-Dependent Signaling from Keratinocytes Promotes Differentiation of Intradermal White Adipocytes.
J Invest Dermatol., 140, 75-84.e6, 2019

4. Ogonuki N, Abe Y, Kurotaki YK, Nakao K, Aiba A, Sasaki E, Ogura A.
Birth of a marmoset following injection of elongated spermatid from a prepubertal male.
Mol Reprod Dev., 86, 928-930, 2019

5. Nakao H, Kishimoto Y, Hashimoto K, Kitamura K, Yamasaki M, Nakao K, Watanabe M, Kano M, Kirino Y, Aiba A.
mGluR1 in cerebellar Purkinje cells is essential for the formation but not expression of associative eyeblink memory.
Sci Rep., 9, 7353, 2019

6. Koebis M, Urata S, Shinoda Y, Okabe S, Yamasoba T, Nakao K, Aiba A, Furuichi T.
LAMP5 in presynaptic inhibitory terminals in the hindbrain and spinal cord: a role in startle response and auditory processing.
Mol Brain., 12, 20, 2019

7. Sakai Y, Kassai H, Nakayama H, Fukaya M, Maeda T, Nakao K, Hashimoto K, Sakagami H, Kano M, Aiba A.
Hyperactivation of mTORC1 disrupts cellular homeostasis in cerebellar Purkinje cells.
Sci Rep., 9, 2799, 2019

2018年
1. Naito R, Kassai H, Sakai Y, Schönherr S, Fukaya M, Schwarzer C, Sakagami H, Nakao K, Aiba A, Ferraguti F.
New Features on the Expression and Trafficking of mGluR1 Splice Variants Exposed by Two Novel Mutant Mouse Lines.
Front Mol Neurosci., 11, 439, 2018

2. Notartomaso S, Nakao H, Mascio G, Scarselli P, Cannella M, Zappulla C, Madonna M, Motolese M, Gradini R, Liberatore F, Zonta M, Carmignoto G, Battaglia G, Bruno V, Watanabe M, Aiba A, Nicoletti F.
mGlu1 Receptors Monopolize the Synaptic Control of Cerebellar Purkinje Cells by Epigenetically Down-Regulating mGlu5 Receptors.
Sci Rep., 8, 13361, 2018

3. Kanayama M, Nakao K, Horie S, Aiba A.
Generation of transgenic mouse line with prostate-specific expression of codon-improved Cre recombinase.
Prostate Int., 6, 99-103, 2018

4. Kubo R, Aiba A, Hashimoto K.
The anatomical pathway from the mesodiencephalic junction to the inferior olive relays perioral sensory signals to the cerebellum in the mouse.
J Physiol., 596, 3775-3791, 2018

5. Kurano M, Tsuneyama K, Morimoto Y, Shimizu T, Jona M, Kassai H, Nakao K, Aiba A, Yatomi Y.
Apolipoprotein M Protects Lipopolysaccharide-Treated Mice from Death and Organ Injury.
Thromb Haemost., 118, 1021-1035, 2018

6. Ogonuki N, Inoue H, Matoba S, Kurotaki YK, Kassai H, Abe Y, Sasaki E, Aiba A, Ogura A.
Oocyte-activating capacity of fresh and frozen-thawed spermatids in the common marmoset (Callithrix jacchus).
Mol Reprod Dev., 85, 376-386, 2018

7. Sudo A, Kanagawa M, Kondo M, Ito C, Kobayashi K, Endo M, Minami Y, Aiba A, Toda T.
Temporal requirement of dystroglycan glycosylation during brain development and rescue of severe cortical dysplasia via gene delivery in the fetal stage.
Hum Mol Genet., 27, 1174-1185, 2018

2017年
1. Kanayama M, Hayano T, Koebis M, Maeda T, Tabe Y, Horie S, Aiba A.
Hyperactive mTOR induces neuroendocrine differentiation in prostate cancer cell with concurrent up-regulation of IRF1.
Prostate, 77, 1489-1498, 2017

2. Nakamura T, Ueyama T, Ninoyu Y, Sakaguchi H, Choijookhuu N, Hishikawa Y, Kiyonari H, Kohta M, Sakahara M, de Curtis I, Kohmura E, Hisa Y, Aiba A, Saito N.
Novel role of Rac-Mid1 signaling in medial cerebellar development.
Development, 144, 1863-1875, 2017.

3. Ueda J, Murata Y, Bundo M, Oh-Nishi A, Kassai H, Ikegame T, Zhao Z, Jinde S, Aiba A, Suhara T, Kasai K, Kato T, Iwamoto K, Use of human methylation arrays for epigenome research in the common marmoset (Callithrix jacchus).
Neurosci Res., 120, 60-65, 2017

4. Ishii T, Ueyama T, Shigyo M, Kohta M, Kondoh T, Kuboyama T, Uebi T, Hamada T, Gutmann DH, Aiba A, Kohmura E, Tohda C, Saito N, A novel Rac1-GSPT1 signaling pathway controls astrogliosis following central nervous system injury.
J Biol Chem., 292, 1240-1250, 2017

5. Endo M, Ubulkasim G, Kobayashi C, Onishi R, Aiba A, Minami Y, Critical role of Ror2 receptor tyrosine kinase in regulating cell cycle progression of reactive astrocytes following brain injury.
Glia, 65, 182-197, 2017



2016年
1. Kikuchi I, Takahashi-Kanemitsu A, Sakiyama N, Tang C, Tang PJ, Noda S, Nakao K, Kassai H, Sato T, Aiba A, Hatakeyama M, Dephosphorylated parafibromin is a transcriptional coactivator of the Wnt/Hedgehog/Notch pathways.
Nat Commun., 7, 12887, 2016

2. Narushima M, Uchigashima M, Yagasaki Y, Harada T, Nagumo Y, Uesaka N, Hashimoto K, Aiba A, Watanabe M, Miyata M, Kano M, The metabotropic glutamate receptor subtype 1 mediates experience-dependent maintenance of mature synaptic connectivity in the visual thalamus.
Neuron, 91, 1097-1109, 2016

3. Nagase M, Kurihara H, Aiba A, Young MJ, Sakai T, Deletion of Rac1GTPase in the myeloid lineage protects against inflammation-mediated kidney injury in mice. PLoS One, 11, e0150886, 2016

4. Ichikawa R, Hashimoto K, Miyazaki T, Uchigashima M, Yamasaki M, Aiba A, Kano M, Watanabe M, Territories of heterologous inputs onto Purkinje cell dendrites are segregated by mGluR1-dependent parallel fiber synapse elimination. Proc Natl Acad Sci USA, 113, 2282-2287, 2016

5. Matsuda I, Shoji H, Yamasaki N, Miyakawa T, Aiba A, Comprehensive behavioral phenotyping of a new Semaphorin 3 F mutant mouse. Mol Brain, 9, 15, 2016

6. Nagahama R, Yamada A, Tanaka J, Aizawa R, Suzuki D, Kassai H, Yamamoto M, Mishima K, Aiba A, Maki K, Kamijo R, Rho GTPase protein Cdc42 is critical for postnatal cartilage development. Biochem Biophys Res Commun., 2016, Epub ahead of print

7. Nakao H, Harada T, Nakao K, Kiyonari H, Inoue K, Furuta Y, Aiba A, A possible aid in targeted insertion of large DNA elements by CRISPR/Cas in mouse zygotes. Genesis, 54, 65-77, 2016

2015年
1. Ayuzawa N, Nagase M, Ueda K, Nishimoto M, Kawarazaki W, Marumo T, Aiba A, Sakurai T, Shindo T, Fujita T, Rac1-Mediated Activation of Mineralocorticoid Receptor in Pressure Overload-Induced Cardiac Injury. Hypertension, 67,99-106, 2015

2. Takenaka N, Sumi Y, Matsuda K, Fujita J, Hosooka T, Noguchi T, Aiba A, Satoh T, Role for RalA downstream of Rac1 in skeletal muscle insulin signalling. Biochem J., 469, 445-54, 2015

3. Mizutani E, Oikawa M, Kassai H, Inoue K, Shiura H, Hirasawa R, Kamimura S, Matoba S, Ogonuki N, Nagatomo H, Abe K, Wakayama T, Aiba A, Ogura A, Generation of cloned mice from adult neurons by direct nuclear transfer. Biol. Reprod., 92, 81, 2015

4. Suzuki W, Yamada A, Aizawa R, Suzuki D, Kassai H, Harada T, Nakayama M, Nagahama R, Maki K, Takeda S, Yamamoto M, Aiba A, Baba K, Kamijo R, Cdc42 is critical for cartilage development during endochondral ossification. Endocrinol., 156, 314-322, 2015

2014年
1. Hamada S, Ogawa I, Yamasaki M, Kiyama Y, Kassai H, Watabe AM, Nakao K, Aiba A, Watanabe M, Manabe T, The glutamate receptor GluN2 subunit regulates synaptic trafficking of AMPA receptors in the neonatal mouse brain. Eur. J. Neurosci., 40, 3136-3146, 2014

2. Ito TK, Yokoyama M, Yoshida Y, Nojima A, Kassai H, Oishi K, Okada S, Kinoshita D, Kobayashi Y, Fruttiger M, Aiba A, Minamino T, A Crucial Role for CDC42 in Senescence-Associated Inflammation and Atherosclerosis. PLoS One, 9, e102186, 2014

3. Takenaka N, Yasuda N, Nihata Y, Hosooka T, Noguchi T, Aiba A, Satoh T, Role of the guanine nucleotide exchange factor in Akt2-mediated plasma membrane translocation of GLUT4 in insulin-stimulated skeletal muscle. Cell Signal, 26, 2460-2469, 2014

4. Kassai H, Sugaya Y, Noda S, Nakao K, Maeda T, Kano M, Aiba A, Selective activation of mTORC1 signaling recapitulates microcephaly, tuberous sclerosis and neurodegenerative diseases. Cell Rep., 7, 1626-1639, 2014 [PubMed][Journal site][プレスリリース]

5. Uesaka N, Uchigashima M, Mikuni T, Nakazawa T, Nakao H, Hirai H, Aiba A, Watanabe M, Kano M, Retrograde Semaphorin Signaling Regulates Synapse Elimination in the Developing Mouse Brain. Science, 344, 1020-1023, 2014

6. Ueyama T, Sakaguchi H, Nakamura T, Goto A, Morioka S, Shimizu A, Nakao K, Hishikawa Y, Ninoyu Y, Kassai H, Suetsugu S, KojiT, Fritzsch B, Yonemura S, Hisa Y, Matsuda M, Aiba A, Saito N, Maintenance of stereocilia and apical junctional complexes by Cdc42 in cochlear hair cells. J Cell Sci., 127, 2040-2052, 2014

7. Takenaka N, Izawa R, Wu J, Kitagawa K, Nihata Y, Hosooka T, Noguchi T, Ogawa W, Aiba A, Satoh T, A critical role of the small GTPase Rac1 in Akt2-mediated GLUT4 translocation in mouse skeletal muscle. FEBS J., 281, 1493-1504, 2014

8. Ohtani Y, Miyata M, Hashimoto K, Tabata T, Kishimoto Y, Fukaya M, Kase D, Kassai H, Nakao K, Hirata T, Watanabe M, Kano M, Aiba A, Synaptic targeting of mGluR1 by carboxyl-terminal domain is crucial for cerebellar function. J Neurosci., 34, 2702-2712, 2014 [PubMed][Journal site]

2013年

1. Torigoe M, Yamauchi K, Tamada A, Matsuda I, Aiba A, Castellani V, Murakami F, Role of neuropilin-2 in the ipsilateral growth of midbrain dopaminergic axons. Eur J Neurosci., 37,1573-1583, 2013

2. Asahara S, Shibutani Y, Teruyama K, Inoue HY, Kawada Y, Etoh H, Matsuda T, Kimura-Koyanagi M, Hashimoto N, Sakahara M, Fujimoto W, Takahashi H, Ueda S, Hosooka T, Satoh T, Inoue H, Matsumoto M, Aiba A, Kasuga M, Kido Y, Ras-related C3 botulinum toxin substrate 1 (RAC1) regulates glucose-stimulated insulin secretion via modulation of F-actin. Diabetologia., 56,1088-1097, 2013

2012年

1. Kato HK, Kassai H, Watabe AM, Aiba A, Manabe T, Functional coupling of the metabotropic glutamate receptor, InsP3 receptor and L-type Ca2+ channel in mouse CA1 pyramidal cells. J Physiol., 590, 3019-3034, 2012

2. Hirata T, Kumada T, Kawasaki T, Furukawa T, Aiba A, Conquet F, Saga Y, Fukuda A, Guidepost neurons for the lateral olfactory tract: Expression of metabotropic glutamate receptor 1 and innervation by glutamatergic olfactory bulb axons. Dev Neurobiol., 72, 1559-1576, 2012

3. Aizawa R, Yamada A, Suzuki D, Iimura T, Kassai H, Harada T, Tsukasaki M, Yamamoto G, Tachikawa T, Nakao K, Yamamoto M, Yamaguchi A, Aiba A, Kamijo R, Cdc42 is required for chondrogenesis and interdigital programmed cell death during limb development. Mech Dev., 129, 38-50, 2012

4. Nishimura S, Manabe I, Nagasaki M, Kakuta S, Iwakura Y, Takayama N, Ooehara J, Otsu M, Kamiya A, Petrich BG, Urano T, Kadono T, Sato S, Aiba A, Yamashita H, Sugiura S, Kadowaki T, Nakauchi H, Eto K, Nagai R, In vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling. Blood, 119, e45-56, 2012

2011年

1. Yamamoto K, Ueta Y, Wang L, Yamamoto R, Inoue N, Inokuchi K, Aiba A, Yonekura H, Kato N, Suppression of a neocortical potassium channel activity by intracellular amyloid-β and its rescue with Homer1a. J Neurosci., 31, 11100-11109, 2011

2. Yamasaki M, Miyazaki T, Azechi H, Abe M, Natsume R, Hagiwara T, Aiba A, Mishina M, Sakimura K, Watanabe M, Glutamate Receptor d2 Is Essential for Input Pathway-Dependent Regulation of Synaptic AMPAR Contents in Cerebellar Purkinje Cells. J. Neurosci., 31, 3362-3374, 2011

2010年

1. Ojima K, Kawabata Y, Nakao H, Nakao K, Doi N, Kitamura F, Ono Y, Hata S, Suzuki H, Kawahara H, Bogomolovas J, Witt C, Ottenheijm C, Labeit S, Granzier H, Toyama-Sorimachi N, Sorimachi M, Suzuki K, Maeda T, Abe K, Aiba A, Sorimachi H, Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy. J. Clin. Invest., 120, 2672-2783, 2010

2. Takeuchi H, Inokuchi K, Aoki M, Suto F, Tsuboi A, Matsuda I, Suzuki M, Aiba A, Serizawa S, Yoshihara Y, Fujisawa H, Sakano H, Sequential arrival and graded secretion of Sema3F by olfactory neuron axons specify map topography at the bulb. Cell, 141, 1056-1067, 2010

3. Ueda S, Kitazawa S, Ishida K, Nishikawa Y, Matsui M, Matsumoto H, Aoki T, Nozaki S, Takeda T, Tamori Y, Aiba A, Kahn CR, Kataoka T, Satoh T, Crucial role of the small GTPase Rac1 in insulin-stimulated translocation of glucose transporter 4 to the mouse skeletal muscle sarcolemma. FASEB J., 24, 2254-2261, 2010

4. Matsuda I, Fukaya M, Nakao H, Nakao K, Matsumoto H, Mori K, Watanabe M, Aiba A, Development of the somatosensory cortex, the cerebellum, and the main olfactory system in Semaphorin 3F knockout mice. Neurosci. Res., 66, 321-329, 2010

2009年

1. Matsumoto H, Kashiwadani H, Nagao H, Aiba A, Mori K. Odor-induced persistent discharge of mitral cells in the mouse olfactory bulb. J. Neurophysiol., 101, 1890-1900, 2009

2. Inoue N, Nakao H, Migishima R, Hino T, Matsui M, Hayashi F, Nakao K, Manabe T, Aiba A, Inokuchi K. Requirement of the immediate early gene vesl-1S/homer-1a for fear memory formation. Mol. Brain., 2:7, 2009

3. Suzuki D, Yamada A, Amano T, Yasuhara R, Kimura A, Sakahara M, Tsumaki N, Takeda S, Tamura M, Nakamura M, Wada N, Nohno T, Shiroishi T, Aiba A, Kamijo R. Essential mesenchymal role of small GTPase Rac1 in interdigital programmed cell death during limb development. Dev. Biol., 335, 396-406, 2009

4. Sakahara M, Ohkawara H, Nakao K, Yokozaki H, Aiba A. The simultaneous induction of tumorigenesis and Cre-loxP recombination in mice. Kobe J. Med. Sci., 54, E279-289, 2009

5. Echigo R, Nakao K, Fukaya M, Watanabe M, Aiba A, Generation of L7-tTA knock-in mice. Kobe J. Med. Sci., 54, E272-278, 2009

6. Bilasy SE, Satoh T, Ueda S, Wei P, Kanemura H, Aiba A, Terashima T, Kataoka T, Dorsal telencephalon-specific RA-GEF-1 knockout mice develop heterotopic cortical mass and commissural fiber defect. Eur. J. Neurosci., 29, 1994-2008, 2009

2008年

1. Ito K, Kawasaki T, Takashima S, Matsuda I, Aiba A and Hirata T. Semaphorin 3F confines ventral tangential migration of lateral olfactory tract neurons onto the telencephalon surface. J. Neurosci., 28, 4414-4422, 2008

2. Kassai H, Terashima T, Fukaya M, Nakao K, Sakahara M, Watanabe M and Aiba A. Rac1 in cortical projection neurons is selectively required for midline crossing of commissural axonal formation. Eur. J. Neurosci., 28, 257-267, 2008

3. Nishino N, Tamori Y, Tateya S, Kawaguchi T, Shibakusa T, Mizunoya W, Inoue K, Kitazawa R, Kitazawa S, Matsuki Y, Hiramatsu R, Masubuchi S, Omachi A, Kimura K, Saito M, Amo T, Ohta S, Yamaguchi T, Osumi T, Cheng J, Fujimoto T, Nakao H, Nakao K, Aiba A, Okamura H, Fushiki T and Kasuga M. FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets. J. Clin. Invest., 118, 2808-2821, 2008

4. Ohtani Y, Harada T, Funasaka Y, Nakao K, Takahara C, Abdel-Daim M, Sakai N, Saito N, Nishigori C and Aiba A, Metabotropic glutamate receptor subtype-1 is essential for in vivo growth of melanoma. Oncogene, 27, 7162-7170, 2008

2007年

1. Nakao H, Nakao K, Kano M and Aiba A. Metabotropic glutamate receptor subtype-1 is essential for motor coordination in the adult cerebellum. Neurosci. Res., 57, 538-543, 2007.

2. Kuwata H, Nakao K, Harada T, Matsuda I and Aiba A. Generation of RGS8 null mutant mice by Cre/loxP system. Kobe J. Med. Sci., 53, 275-281, 2007.

3. Aiba A and Nakao H. Conditional mutant mice using tetracycline-controlled gene expression system in the brain. Neurosci. Res., 58, 113-117, 2007

4. Tabata T, Kawakami D, Hashimoto K, Kassai H, Yoshida T, Hashimotodani Y, Fredholm BB, Seikno Y, Aiba A and Kano M. G protein-independent neuromodulatory action of adenosine on metabotropic glutamate signaling in mouse cerebellar Purkinje Cells. J. Physiol., 581, 693-708, 2007.

5. Aiba A, Inokuchi K, Ishida Y, Itohara S, Kobayashi K, Masu M, Mishina M, Miyakawa T, Mori H, Nakao K, Obata Y, Sakimura K, Shiroishi T, Wada K, Yagi T. Mouse liaison for integrative brain research. Neurosci. Res., 58, 103-104, 2007

6. Yoshikawa Y, Satoh T, Tamura T, Wei P, Bilasy SE, Edamatsu H, Aiba A, Katagiri K, Kinashi T, Nakao K, Kataoka T. The M-Ras-RA-GEF-2-Rap1 pathway mediates tumor necrosis factor-a dependent regulation of integrin activation in splenocytes. Mol. Biol. Cell, 18, 2949-2959, 2007

7. Wei P, Satoh T, Edamatsu H, Aiba A, Setsu T, Terashima T, Kitazawa S, Nakao K, Yoshikawa Y, Tamada M, Kataoka T. Defective vascular morphogenesis and mid-gestation embryonic death in mice lacking RA-GEF-1. Biochem. Biophys. Res. Commun., 363, 106-12, 2007

2005年

1. Kassai H, Aiba A, Nakao K, Nakamura K, Katsuki M, Xiong WH, Yau KW, Imai H, Shichida Y, Satomi Y, Takao T, Okano T and Fukada Y. Farnesylation of retinal transducin underlies its translocation during light adaptation. Neuron, 18, 529-539.

2. Maejima T, Oka S, Hashimotodani Y, Ohno-Shosaku T, Aiba A, Wu D, Waku K, Sugiura T, Kano M. Synaptically driven endocannabinoid release requires Ca2+-assisted metabotropic glutamate receptor subtype 1 to phospholipase Cbeta4 signaling cascade in the cerebellum. J. Neurosci., 25, 6826-6835.

3. Tomemori Y, Ichiba M, Kusumoto A, Mizuno E, Sato D, Muroya S, Nakamura M, Kawaguchi H, Yoshida H, Ueno S, NakaoK, Nakamura K, Aiba A, Katsuki M, and Sano A. A gene-targeted mouse model for chorea-acanthocytosis. J. Neurochem., 92, 759-766.

2004年

1. Kuwajima M, Hall R A, Aiba A, and Smith Y. Subcellular and subsynaptic localization of group I metabotropic glutamate receptors in the monkey subthalamic nucleus. J. Comp. Neurol., 474, 589-602.

2. Nakamura M, Sato K, Fukaya M, Araishi K, Aiba A, Kano M and Watanabe M. Signaling complex formation of phospholipase Cbeta4 with metabotropic glutamate receptor type 1alpha and 1,4,5-tris-phosphate receptor at the perisynapse and endoplasmic reticulum in the mouse brain. Eur. J. Neurosci., 20, 2929-2944.

2003年

1. Chida K, Hara T, Hirai T, Konishi C, Nakamura K, Nakao K, Aiba A, Katsuki M, and Kuroki T. Disruption of protein kinase Ceta results in impairment of wound healing and enhancement of tumor formation in mouse skin carcinogenesis. Cancer Res., 63, 2404-2408.

2002年

1. Kishimoto Y, Fujimichi R, Araishi K, Kawahara S, Kano M, Aiba A, Kirino Y. mGluR1 in cerebellar Purkinje cells is required for normal association of temporally contiguous stimuli in classical conditioning. Eur. J. Neurosci., 16, 2416-2424.

2. Muto S, Aiba A, Saito Y, Nakao K, Nakamura K, Tomita K, Kitamura T, Kurabayashi M, Nagai R, Higashihara E, Harris PC, Katsuki M and Horie S. Pioglitazone improves the phenotype and molecular defects of a targeted Pkd1 mutant. Hum. Mol. Genet., 11, 1731-1742.

3.Tabata T, Aiba A and Kano M. Extracellular calcium controls the dynamic range of neuronal metabotropic glutamate receptor responses. Mol. Cell. Neurosci., 20, 56-68.

4.Shutoh F, Katoh A, Kitazawa H, Aiba A, Itohara S and Nagao S. Loss of adaptability of horizontal optokinetic response eye movements in mGluR1 knockout mice. Neurosci. Res., 42, 141-145

2001年

1. Hashimoto K, Ichikawa R, Takechi H, Inoue Y, Aiba A, Sakimura K, Mishina M, Hashikawa T, Konnerth A, Watanabe M, and Kano M. Roles of glutamate receptor d2 subunit (GluRd2) and metabotropic glutamate receptor subtype 1 (mGluR1) in climbing fiber synapse elimination during postnatal cerebellar development. J. Neurosci., 21, 9701-9712.

2. Takeuchi T, Kiyama Y, Nakamura K, Tsujita M, Matsuda I, Mori H, Munemoto Y, Kuriyama H, Natsume R, Sakimura K and Mishina M. Roles of the glutamate receptor e2 and d2 subunits in the potentiation and prepulse inhibition of the acoustic startle reflex. Eur. J. Neurosci., 14, 153-160.

3. Maejima T, Hashimoto K, Yoshida T, Aiba A and Kano M. Presynaptic inhibition caused by retrograde signal from metabotropic glutamate to cannabinoid receptors. Neuron, 31, 463-475.

2000年

1. Matsuda I and Mishina M. Identification of a juxtamembrane segment of the glutamate receptor delta2 subunit required for the plasma membrane localization. Biochem. Biophys. Res. Commun., 275, 565-571.

2. Manabe T, Aiba A, Yamada A, IchiseT, Sakagami H, Kondo H and Katsuki M. Regulation of long-term potentiation by H-Ras through NMDA receptor phosphorylation. J. Neuorsci., 20, 2504-2511.

3. Ise K, Nakamura K, Nakao K, Shimizu S, Harada H, Ichise T, Miyoshi J, Gondo Y, Ishikawa T, Aiba A and Katsuki M. Targeted deletion of the H-ras gene decreases tumor formation in mouse skin carcinogenesis. Oncogene,19, 2951-2956.

4. Ichise T, Kano M, Hashimoto K, Yanagihara D, Nakao K, Shigemoto R, Katsuki M and Aiba A. mGluR1 in cerebellar Purkinje cells essential for long-term depression, synapse elimination, and motor coordination. Science, 288, 1832-1835.

1999年

1. Sugiyama T, Hirono M, Suzuki K, Nakamura Y, Aiba A, Nakamura K, Nakao K, Katsuki M and Yoshioka T. Localization of phospholipase Cbeta isozymes in the mouse cerebellum. Biochem. Biophys. Res. Commun., 265, 473-478.

1998年

1. Sugihara K, Nakatsuji N, Nakamura K, Nakao K, Hashimoto R, Otani H, Sakagami H, Kondo H, Nozawa S, Aiba A and Katsuki M. Rac1 Is required for the formation of three germ layers during gastrulation. Oncogene, 17, 3427-3433.

1997年

1. Kano M, Hashimoto K, Kurihara H, Watanabe M, Inoue Y, Aiba A and Tonegawa S. Persistent multiple climbing fiber innervation of cerebellar Purkinje cells in mice lacking mGluR1. Neuron, 18, 71-79.

2. Koera K, Nakamura K, Nakao K, Miyoshi J, Toyoshima K, Hata T, Otani H, Aiba A and Katsuki M. K-Ras Is essential for the development of the mouse embryo. Oncogene, 15, 1151-1159.

1996年

1. Yamaguchi H, Aiba A, Nakamura K, Nakao K, Sakagami H, Goto K, Kondo H and Katsuki M. Dopamine D2 receptor plays a critical role in cell proliferation and proopiomelanocortin expression in the pituitary. Genes Cells, 1, 253-268.

1995年

1. Hsia AY, Salin PA, Castillo PE, Aiba A, Abeliovich A, Tonegawa S and Nicoll RA. Evidence against a role for metabotropic glutamate receptors in mossy fiber LTP: the use of mutant mice and pharmacological antagonists. Neuropharmacol., 34, 1567-1572.

2. Kano M, Hashimoto K, Chen C, Abeliovich A, Aiba A, Kurihara H, Watanabe M, Inoue Y and Tonegawa S. Impaired synapse elimination during cerebellar development in PKCgamma mutant mice. Cell, 83, 1223-1231.

1994年

1. Aiba A, Chen C, Herrup K, Rosenmund C, Stevens CF, Tonegawa S. Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice. Cell, 79, 365-375.

2. Aiba A, Kano M, Chen C, Stanton ME, Fox GD, Herrup K, Zwingman TA, Tonegawa S. Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice. Cell, 79, 377-388.

©2009 Laboratory of Animal Resouces, Center for Disease Biology and Integrated Medicine, Graduate School of Medicine, The University of Tokyo